Scientist I, Infectious Diseases
Company: Modex Therapeutics Ltd.
Location: Weston
Posted on: March 25, 2026
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Job Description:
Company Overview ModeX Therapeutics, an OPKO Health company, is
the leading clinical-stage biopharmaceutical company developing
unique and proprietary-multispecific therapeutics. Its MSTAR
platform unites the power of multiple biologics in a single
molecule to create multispecific antibodies that bind four or more
targets with unprecedented versatility and potency for complex
diseases. Its promising first-in-class immunology pipeline includes
candidates against immune diseases, including cancer (both solid
and hematologic tumors), immune impairment, as well as several of
the world's most pressing viral threats. Its founding team includes
globally recognized medical innovators with proven track records of
delivering breakthroughs for patients. ModeX is based in Weston,
Massachusetts. For more information, please visit www.modextx.com .
Job Description ModeX Therapeutics is seeking a motivated scientist
with experience in molecular biology. They will be part of a
dynamic team focusing on developing innovative biotherapeutics for
treating infectious diseases. The primary responsibilities of the
position are to work with senior team members to design DNA
constructs, produce proteins, maintain cell lines, perform
biological assays, and coordinate CROs. This is an exciting
opportunity to be part of a cross-functional team and contribute to
the development of next-generation synthetic biotherapeutics in a
fast-paced, rapidly growing biotech company with a bold vision. Key
responsibilities include but are not limited to: Support the
molecular cloning pipeline, including DNA silico analysis, codon
optimization, gene fragment assembly, cloning and production of
transfection grade plasmids. Transfection, expression, and
purification of proteins from mammalian cells using endotoxin free
methods. Perform in vitro biochemical and biophysical
characterizations of protein candidates, including techniques like
ELISA, Octet, DLS, SDS-PAGE, and Western Blot. Production of
lentiviral based pseudovirus stocks. Test activity of antibodies in
pseudovirus neutralization assays. Help design and coordinate
studies with CROs. Proficient in independently addressing and
resolving experimental problems. Exceptional organizational,
technical, and troubleshooting skills, with keen attention to
detail and sterile technique. Careful and thorough recording of
experimental data using an electronic lab notebook. Analyze data
using appropriate software and statistical methods, and clear
reporting of results to the team. Work both independently and
collaboratively as part of a project team. Qualifications PhD with
0-1 yrs industry experience in infectious disease, virology,
molecular biology, protein biochemistry, or related field.
Knowledge and hands on experience in molecular cloning, cell
culture and biological assays. Protein purification experience.
Experience working with mammalian cells and good sterile technique.
Familiarity with the production and characterization of antibodies.
Excellent written and communication skills for collaborating with
team members and presenting data. Highly adaptable to a fast-paced
work environment and can efficiently prioritize tasks and manage
time. ModeX Therapeutics is an Equal Opportunity Employer
Keywords: Modex Therapeutics Ltd., East Providence , Scientist I, Infectious Diseases, Science, Research & Development , Weston, Rhode Island
